I thought the whole idea was to show that the wizard is impervious? Not to give the opposition some sort of comic book style chance to stop us.
That's the exact kind of clarity that I think this thread needs.
Initially, this was just a more-or-less typical "need anti-caster build" thing, but unlike many others that have died off, there seems to be enough interest to keep this thread alive.
So, maybe to clarify - a typical totally paranoid wizard is definitely impervious (as per Genesis, etc, and stacking the deck as they see fit). But I also think that their impact on anything significant is ridiculously reduced, so they aren't really an issue.
So, what does that leave? A wizard could probably be sniped under some circumstances when they leave, so I've taken the pro-mundane side in trying to provide problems that the wizard would need to deal with (like before, on the Mindsight issue - wiz needs 24 h Truesight).
EDIT: but we STILL don't really have parameters. I like to think of the problem as "I have a wizard in the party that I want to kill, in a real game" vs. "I am a wizard whom someone wants to kill, in my own game, but I'm not sure what I need to do to prevent it (while still being the party wiz)."