Something that I'm doing in my current campaign (which was inspired by one of the PCs in my last one):
Make prolific use of the Mother Cyst spells (LM).
Necrotic Cyst is at the heart of it (of course).
Necrotic Tumor, with carefully worded instruction to not violate
OPSEC is very useful for not being caught to begin with. It also prevents someone from extracting information from your operatives.
Craft Contingency is also pretty awesome. (because of time and costs constraints) Use "craft contingency" to hit-up your
key operatives with a Necrotic Eruption or Necrotic Termination, in the event that OPSEC get's potentially compromised.
This has become a major focal point for my current campaign -- while the PCs are becoming frustrated (and have definitely compromised their morals and ethics when dealing with it), the players just love the insidiousness of it.