such as they didnt mention epi stuff related to non animals. i assume plants, bacteria and the like also have the epi markers
I'm sure plants do. Bacteria certainly have methylation systems, but those are often part of the bacteria's defense system for destroying foreign DNA. I don't know if they use them in the same way eukaryotes do (in gene regulation). Lots of bacteria have enzymes that cut DNA at certain sequences, and their methylation system makes sure that these enzymes don't cut up their own DNA.
is it reasonable / feasible to strip all epi markers from the genes and grow the thing as a clean slate or are these markers a fundamental thing for making the machine work?
They seem to be fundamental. Craig Venter's research group has tried to remove the DNA from an organism and replace it with synthetically created DNA. This didn't work originally, and I suspect it is because it was missing epigenetic factors. I don't recall if they've succeeded at this yet. I think they got closer, but not quite all the way.
what are these drugs that strip epi markers, do they clean the whole slate or just certain markers? hows bout adding markers?
I'm not sure. I'd have to know the specific drug and markers.
i didnt see that they described the composition of the markers, like the ctag of dna..
Methylation and DNA packaging are the main two (that I know of), which probably are not unrelated.
in conclusion, im glad im not a geneticist...
I have a BS in recombinant genetics, but I don't study this stuff specifically. My brother and law does, though.