El Abuelo, all the way! Nazi's are the endgame, cannibals the obnoxious bastards we may encounter one more time (hopefully I'll be able to convince them to go after the nazi's, heheheh), but El Abuelo is one of those side-quest/mini-endboss things that I think would be hella fun. Cannibals? Eisen hates to bother himself with. Nazi's? That's just fuckin' fun for a guy like Eisen. El Abuelo? That's got some character development/altering of perception going for it.
Also, I'm damn glad we have someone like jolt to actually put clues together, cause I sure as hell ain't keeping up with it, lol.